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"This project will enable precision measurements of the physical, chemical and biological changes that occur when cells are subjected to mechanical loading, ranging from small perturbations to high-force, high-speed impacts," said Megan Valentine from UC Santa Barbara.."Our technology will provide significantly higher forces and faster impact cycles than have previously been possible, and by building these tools onto microfluidic devices, we can leverage a host of other on-chip diagnostics and imaging tools and can collect the cells after testing for longer-term studies," said Valentine.It may also lead to better prevention of such injuries by elucidating, for instance, what types of forces affect the neural cells most so helmets can be designed to buffer them.Modelled after cell-sorting technology used typically for medical diagnostics and immunotherapies, the MicroHammer flows individual cells through and subjects each of them to one of a variety of physical forces. Far from being isolated units of life, cells - stem cells in particular - take cues from their environment that, for example, direct them to differentiate into one type of cell or another, or to start healing processes.

The knowledge gained by these experiments could pave the way toward a better understanding of neural conditions such as Alzheimers disease as well as traumatic brain injury.The MicroHammer is currently undergoing the process of characterisation, whereby the types and magnitudes of forces it can apply are being measured and recorded in anticipation of the first set of neuron-smashing experiments. It will have broad applications beyond brain cell research and help researchers gain insight on China CNC spring making machine Manufacturers how forces affect other cells and tissue types. "Mechanical forces have been shown to impact cells a lot," said Kimberly Tuer from UC Santa Barbara. With the new devices and methods, Valentine said, the researchers expect to gain fundamentally new insight into the causes and progress of brain injuries due to trauma.Los Angeles: Researchers have created worlds tiniest hammer to precisely measure how force affects brain cells, an advance that may pave the way for better treatments against traumatic brain injuries and diseases like Alzheimers.Researchers at University of Califoia, Santa Barbara in the US have built a tiny machine called microHammer. MicroHammer, a cellular-scale machine built to tap, strike, squeeze and poke individual neural progenitors elicits responses that will then be studied and recorded to add to a body of knowledge that can help unlock the mysteries of the brain.However a major limitation to understanding the reactions of individual neural cells to forces has been the inability to reliably apply impact or pressure to them。

Analysts told AFP that Apple was in position to fend off the blow from the EU demand that the iPhone maker pay a record 13 billion euros ($14.The commission ruled that Apple had received favorable tax terms that amounted to state aid — illegal under its rules.South Korean consumer electronics giant LG is set to show off a new premium V20 smartphone in San Francisco the evening before the Apple event.Improved iPhone and smartwatch models would be arriving just as Apple is set to roll out a new version of the mobile operating system.

Apple Watch time Califoia-based Apple could also use the event to showcase updates to other products, such as its smartwatch and laptop computers."Apple is a company that lived hit to hit: the iPod, iPhone, iPad," said independent Silicon Valley analyst Rob Enderle of Spring grinding machine Suppliers Enderle Group."Analysts and Apple fans have been eagerly waiting for Cook to take a page from Jobs's playbook and enthrall the world with a must-have "one more thing."Apple iPhones have been at the heart of the company's money-making machine for years, while reported investments in self-driving cars and virtual reality have yet to result in transformative new products.Apple is moving into new areas such as Apple TV and streaming music, which could produce more stable revenues.5 billion) in back taxes in Ireland.Apple has maintained a rhythm of introducing updated iPhone models on an annual basis, timing introductions to coincide with the year-end holiday shopping season."It's total political crap," Cook told the Irish Independent newspaper, of European Competition Commissioner Margrethe Vestager's assertion that the company had paid a tax rate of 0.To assuage users accustomed to wired headphones, Apple could roll out accessories that include an adaptor that plugs into a remaining port.005 per cent on its European profits in 2014.Apple iPhones have been at the heart of the company's money-making machine for years.The event on Wednesday will come as Apple squares off with the European Union over a multibillion-dollar bill.With iPhone sales and profits sliding, Apple in July highlighted growth in sales of apps, music and cloud services.Apple reported a drop in iPhone sales in the second quarter of this year, a second straight drop after uninterrupted growth since its introduction in 2007.The event would also be a chance to showcase wireless headphones, perhaps some from Beats, which Apple bought two years ago in a deal valued at $3 billion.In July, the company announced the sale of its billionth iPhone, a milestone for the company as it seeks to keep momentum in a competitive smartphone market.Of that total, $214."

Without those successive hits, it is struggling.5 billion in cash plus marketable securities at the end of June.Apple is expected to unveil a new iPhone and maybe even a second-generation smartwatch at a special event in San Francisco on September 7.The rumor mill has been grinding away with talk of iPhone 7 models that will boast faster chips, more sophisticated cameras, and improved software while doing away with jacks for plugging in wired headphones.8 billion, or 93 per cent, was said to be outside the United States, Apple's chief financial officer Luca Maestri said on an eaings call.The V20 will be the first to ship with a new Nougat version of Google-backed Android operating software.

In the Apple's usual enigmatic style, it provided little more that the date, time and place to the invitation-only gathering.Speculation regarding an Apple Watch 2 was fuelled in part by the fact that the original hardware has not been updated since it debuted in April of last year.Apple has vowed to fight the tax bill.Apple expects to repatriate billions of dollars of global profits to the United States next year, Cook told Irish national broadcaster RTE without providing specific figures.. While it has plenty of cash, it has stopped being a market maker.According to its most recent eaings report, Apple had $231.The ease with which the company could write a check to pay the gargantuan bill was seen as potentially coming back to bite Apple by giving the impression it is greedily avoiding doing right by the public coffers.Meanwhile, leading smartphone maker Samsung has announced it will recall its latest flagship smartphone after faulty batteries caused some Galaxy Note 7 "phablets" to explode while charging, in a massive blow to the South Korean electronics giant's reputation.New hit neededApple's real issue is the lack of a blockbuster announcement along the lines of those that ignited markets and rocketed the company to glory under the leadership of late co-founder Steve Jobs, according to analysts.

There is a heavy ‘clank’ when you engage first gear and in no time, you’re in the chunk of the torque band. Whether it’s the Triumph logo headlamp bulb cover or the brand insignia on the spark plug leads and foot pegs, there’s evidence that the designers took their time while putting pen to paper.Triumph has somehow pulled it off and the T120 is still a perfect blend of retro and mode design. It's an unassuming and easy to ride motorcycle that can please the seasoned among us while nurturing a novice.Triumph has somehow pulled it off and the T120 is still a perfect blend of retro and mode design.Overall though, the engine is one of the reasons why the Bonneville makes for a great upgrade if you already own a middleweight.

That's why I respect the Bonneville, and with the T120, the Brits have attempted to give it an entirely new life.The T120 is still a neutral handler, though we didn’t get to push it to its limits due to heavy rains.While premium motorcycles are usually loud and brash, the Bonneville has defined the term 'hiding in plain sight’. While the 224kg (dry) weight doesn’t really show around twisties or on the open road, the T120 does warrant a little effort in the city.Have they succeeded, or is this a distinction without a difference Time to find out!Design & FeaturesEver so often, along comes a model with a cult-like loyalty base. You can hit north of 140kmph with a lot more ease, but it’s easy to tell that the engine is most comfortable cruising around 100-120kmph.The Triumph Bonneville is a very special bike to me.The T120 is supposed to be inspired by the original 1959 Bonneville, but honestly, there’s not much by way of similarities. They’ve worked to fix old flaws and added a lot of firsts for the age-old nameplate. The reason is that it was the first twin-cylinder motorcycle I ever drove. The rear brake, on the other hand, needs more bite and feels wooden.

The faux carburettors hide fuel injectors that now get ride-by-wire, and the new throttle system has also enabled integration of ride modes (road/rain). That said, the Bonneville is still an approachable machine to ride, even with it now entering litre-class territory, provided you understand that it can throw you back into the pillion seat if you get too ambitious.New generation updates usually see minor output changes, but Triumph has gone for an all-out overhaul. However, you can easily lean in at sharp angles and glide through coers all day long. Triumph has done well by giving it some much-needed updates, while doing little to tick off the loyalists. Due credit to the slightly raised spring travel at the rear which makes it more pillion friendly.Engine & PerformanceThe Bonneville may attribute its name to a holy land of speed, but today, it's best known for relaxed riding and mature torque delivery. What you do get, though, is improved quality levels and a lot of attention to detail. It was also for the first time when I was riding a bike having an engine of more than 500cc and it made me feel very special. That said, you can switch to rain mode to tame the delivery, and the traction control doesn’t intervene unless you twist the throttle like a hooligan. The round headlamp gets integrated DRLs and the twin-pod instrument cluster isn’t as bulbous anymore. Like the traction control system, the ABS isn’t too intrusive either and the setup does trust your judgement. Its price-rivals are both too mode and sporty (Kawasaki Z800, Ducati Monster 821) or too conspicuous (Harley-Davidson 1200 Custom) for the traditional British classic buyer. I’m happy to say that the ride quality has improved, with the 41mm front forks and twin (pre-load adjustable) rear shocks making the T120 more compliant than ever before. There are alteatives with more titillating on paper numbers, but few that give you performance that’s as usable.

Its mannerisms are quite tourer-like in that way, though there is a good amount of buffeting at triple digit speeds. The Bonneville is noticeably front heavy and the steering isn’t a ‘point and shoot’ affair.Flickable Afraid not. The front brakes offer progressive bite and are confidence-inspiring even in the rain, but there is a lack of feedback.70 lakh (ex-showroom, Delhi), it’s an affordable litre-classer that falls into a niche within a niche. The riding posture is relaxed and the 785mm seat height will be comfortable for the average-heighted as well. Apart from these personal reasons, there are other reasons why this bike is called 'legendary'. The 'high-torque’, 8-valve, 1,200cc parallel-twin engine produces 80PS of power and 105Nm of torque (vs the old 865cc’s 68PS and 68Nm), both of which are delivered earlier in the rev range as well. It won’t be the first choice for younger audiences, but for the middle-aged rider who is looking for a mature, sensible and understated package that can misbehave when asked to, it’s hard to do much better. It works well at slow speeds but I found myself primarily using it to balance out any hard braking inputs at the front on the highway. Instead of the old Metzelers, it now rides on Pirelli Phantoms which offer good dry weather grip. Before riding through the lush greens of NH4, the bike was taken through disturbingly damaged roads, and not once did it bottom-out, even with my heavy frame weighing it down.Hit the starter and the motor cranks to spring bending machine Manufacturers life with a bassy burble, typical of British classics.

Additional goodies include heated grips as standard (I hear the Ladakh lot celebrating already), a USB charging socket under the seat and an LED tail light, which complete the old-timer’s modeization. Liquid-cooling does a great job of heat dissipation at speeds and in moving traffic, but get caught in a crawl and the radiator does blow hot air straight at your shins. You still get analogue instrumentation, but it’s complemented by LCD displays that read out data like the fuel level, trip meter, distance-to-empty and fuel efficiency. The engine encourages low rev upshifts and thanks to the impeccable mid-range, overtakes don’t command a downshift.The 6-speed gearbox is uber-slick and while the rev-happy engine is sprightly in city, getting even a little generous with the throttle sends the T120 surging ahead into triple digit speeds. Vibration is well-managed and, as expected, getting off the mark doesn’t need much throttle input. It still offers performance that is usable and approachable, along with a design that is timeless, subtle, and quintessentially British. Even the radiator has been painted in the most devil-pleasing shade of black to hide it from view. These fans do not take kindly to major changes and the Bonneville's designers faced a similar problem - make it look different so it isn't a case of old wine in a new bottle, but not so much that the fanboys cry 'anarchy’. While they’re great on rain-lashed highways as well, things do get a bit tricky in coers as the torque tends to be a bit much for the tyres to handle on wet tarmac.It does, however, take a keen eye to spot the differences vs the old model since the fuel tank, side panels and seat look quite similar.VerdictThe T120 is still the well-rounded package you’d expect a Bonneville to be.com.While the 18-inch front and 17-inch rear wheels get a classic spoke layout, they’re adoed by disc brakes that get not only ABS but switchable traction control as well. What's more interesting is that it even gets liquid-cooling.Ride, Handling & BrakingOne of my complaints with the old Bonneville was its stiff suspension setup. The tuing radius is quite large as well, but come on, it’s not exactly a commuter, is it Stopping power comes from twin 310mm discs up front and a single 255mm disc at the rear. That said, the relatively minor changes hide a lot of new tech that’s been added to the T120.So with the uprated output, is the improved performance noticeable Yes, of course, but just don’t straddle the bike expecting an earth-shattering difference. You can have a good amount of fun before you even cross 2,000rpm. At a price of Rs 8. The clutch latches on quickly and while it’s not the lightest around, city riding is no hassle.

"It is the day to remember every jawan who maintains law and peace in Jammu and Kashmir and fights against terrorism.Hours before inaugurating the memorial, PM Modi tweeted: "A grateful nation pays tributes to all those policemen and policewomen martyred in the line of duty. Jawans on duty in Naxal-affected areas are doing a great service. We salute their families for their fortitude.Union Home Minister Rajnath Singh and senior BJP leader L K Advani also paid homage to the martyred policemen.The Prime Minister also honoured the survivors of the Hot Spring incident.Over 34,000 police personnel have been killed in action till now in the country and during the last about one year time (September 1, 2017 to October, 31 this year) a total of 414 personnel have laid down their lives or died due to unnatural reasons, a latest data said. He also paid tributes to the policemen killed in an ambush by Chinese troops in 1959 at Hot Spring area in Ladakh.

The family members of the personnel who died in the line of duty were invited to the Spring making machine Suppliers event, officials said. Prime Minister Narendra Modi on Sunday dedicated the refurbished National Police Memorial, including a newly built museum of these forces, to the nation on the occasion of police commemoration day.On the occasion, Prime Minister Narendra Modi also remembered the soldiers, who are on duty in Jammu and Kashmir and Naxal-hit areas and lauded their efforts."Ministers of state in the Home Ministry Kiren Rijiju and Hansram G Ahir, National Security Advisor (NSA) Ajit Doval along with senior officers and personnel of various Central Armed Police Forces (CAPFs) and state police forces were present during the event.25-lakh personnel strong paramilitary has been the recipient of the maximum gallantry awards over the years for action in Naxal violence hit and militancy affected areas of Jammu and Kashmir and north easte states, news agency PTI reported.12 acres of land in Chanakyapuri, at the northe end of Shanti Path and it represents all state and union territories police forces as well as central police organisations of the country. The peace prevalent in the nation is possible only due to your services," the Prime Minister said.Addressing the gathering at National Police Memorial, PM Modi hailed the police personnel for their efforts in ensuring peace in the country.Earlier, CRPF Director General R R Bhatnagar said that the about 3.

The attempts to create fear and insecurity in the nation were foiled by you.The memorial has been erected on 6..The national police museum depicts the history, artefacts, uniform and gear of central and state police forces. Its also due to them that the number of Naxal affected districts is going down and the youth is coming to the mainstream," he said."It is the result of your (police) alertness that the elements which create unrest are unsuccessful in their attempts。